ANGSD: Analysis of next generation Sequencing Data
Latest tar.gz version is (0.938/0.939 on github), see Change_log for changes, and download it here.
User:Thorfinn
- Thetas,Tajima,Neutrality test needs documentation and examples files
- doMajorMinor 4 fjerner sites som ikke har major/minor som ref. total maerkeligt og fucked up
- user custom class missing
- -samglfclean not documented
- soap usage is not documented
- -sites does not work without all chromsomes being in the *sites file
- -sites gives wrong chromomosome in error
- phat does not work alone (-doMaf 8)
- make haploid 1dsfs
- fix wiki doc with -sites should contain -rf with curs from -sites
- describe -trim! does trim 3 remove the first and last 3 bases? or just 2?
- from morten shitoutput
h1 h2 h3 = 7 10 5 has less than 3 blocks. skipping h1 h2 h3 = 8 10 5 has less than 3 blocks. skipping h1 h2 h3 = 10 11 5 has less than 3 blocks. skipping h1 h2 h3 = 7 12 5 has less than 3 blocks. skipping h1 h2 h3 = 10 12 5 has less than 3 blocks. skipping h1 h2 h3 = 10 13 5 has less than 3 blocks. skipping h1 h2 h3 = 10 15 5 has less than 3 blocks. skipping h1 h2 h3 = 7 10 6 has less than 3 blocks. skipping h1 h2 h3 = 8 10 6 has less than 3 blocks. skipping h1 h2 h3 = 9 10 6 has less than 3 blocks. skipping h1…
- fix -doFasta for single chromosomes. put gzwrite && bufstr.l =0 whenever we change cur
- -doMaf 4 is not working if post is not external
- Regarding an open issue of printing %e instead o numbers, using the bombyx/lyca dataset:
- fix }else{
fprintf(stderr,"./a.out [make_bed|do_stat|validate_bed|print]\n"); } in thetaStat
- simplefy filereading. from glf files
- check 1offseted in -sites file
- add more info to -sites file output
- better screen output if unsorted filtering
Anders changes to version 583
1) Default minMaf set to -1 (instead of 0)
2) added
freqs->freq = new double[pars->numSites];
to phatLoop
added the if part of if(freq->freq==NULL)
freq->freq = new double[pars->numSites];
to postFreq and likeFreq funcitons to stop leak + be able to run phat without postFreq/likeFreq
3) changed doMajorMinor 2 to choose a minor allele even if no minor allele is observed (if -minMaf is chosen the site will be removed). This avoid removing side through the majorMinorMod function. The change else if (bases[i]>temp){ -> else if (bases[i]>=temp){ in majorMinorCounts
4) Estimate nInd even if -minInd 0. Else the output is wrong when -minInd 0 filter::run changed
e.g.
$ANG -out out -doMajorMinor 2 -doMaf 8 -bam bam.filelist -doCounts 1 -r 1: before gunzip -c out.mafs.gz | headchromo position major minor phat nInd
1 13999919 A T 0.000000 10
1 13999920 G T 0.000000 10
1 13999921 G T 0.000000 10
1 13999922 C T 0.000000 10
after chromo position major minor phat nInd
1 13999919 A T 0.000000 1
1 13999920 G T 0.000000 1
1 13999921 G T 0.000000 1
1 13999922 C T 0.000000 1
1 13999923 A T 0.000000 1
(there is only information for one individual)