ANGSD: Analysis of next generation Sequencing Data

Latest tar.gz version is (0.938/0.939 on github), see Change_log for changes, and download it here.

Fst PCA

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Revision as of 12:55, 25 June 2013 by Thorfinn (talk | contribs)
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Matteo Fumagalli has been working on methods to estimate Fst and doing PCA based on ANGSD output files.

Fst

  1. Generate .sfs files from each population using ANGSD RealSFS
  2. Estimate the .sfs.ml or .sfs.em.ml for each .sfs file
    1. using a 2D-SFS as a prior, estimated using ngs2dSFS
    2. using marginal spectra as priors, estimated using optimSFS
    3. here we don't provide prior files, so we directly provide posterior probabilities (ANGSD+sfstools), and therefore we do not correct