ANGSD: Analysis of next generation Sequencing Data

Latest tar.gz version is (0.938/0.939 on github), see Change_log for changes, and download it here.

HWE and Inbreeding estimates: Difference between revisions

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Filipe G. Vieira  has been extending the ANGSD feature set by a very fancy method for estimating individual inbreeding coefficients.
Filipe G. Vieira  has been extending the ANGSD feature set by a very fancy method for estimating individual inbreeding coefficients.
Please see his website here: https://github.com/fgvieira/ngsF for the latest version which is utilising ANGSD output
Please see his website here: https://github.com/fgvieira/ngsF for the latest version which is utilising ANGSD output
;NB If in doubt if a specific analysis will work with inbreeding send an email.

Revision as of 12:50, 28 February 2014

ANGSD can estimate the 'F' on a single site basis.

-HWE_pval

By choosing HWE_pval 1, no sites will be filtered but the p-value along wight the frequency, and F for the sites will be dumped in .hwe.gz file.

Some parts of the ANGSD code (site frequency-sample allele frequency using genotype likelihoods) will work for inbreeding estimates version 0.572+. Downstream analysis that are using frequencies will therefore work.

Filipe G. Vieira has been extending the ANGSD feature set by a very fancy method for estimating individual inbreeding coefficients. Please see his website here: https://github.com/fgvieira/ngsF for the latest version which is utilising ANGSD output