ANGSD: Analysis of next generation Sequencing Data

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Fst PCA: Difference between revisions

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(Created page with "Matteo Fumagalli has been working on methods to estimate Fst and doing PCA based on ANGSD output files. =Fst= # Generate .sfs files from each population using ANGSD [[RealSFS...")
 
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=Fst=
=Fst=
# Generate .sfs files from each population using ANGSD [[RealSFS]]
# Generate .sfs files from each population using ANGSD [[RealSFS]]
#
# Estimate the .sfs.ml or .sfs.em.ml for each .sfs file
## using a 2D-SFS as a prior, estimated using ngs2dSFS
## using marginal spectra as priors, estimated using optimSFS
## here we don't provide prior files, so we directly provide posterior probabilities (ANGSD+sfstools), and therefore we do not correct
 
 
##

Revision as of 12:55, 25 June 2013

Matteo Fumagalli has been working on methods to estimate Fst and doing PCA based on ANGSD output files.

Fst

  1. Generate .sfs files from each population using ANGSD RealSFS
  2. Estimate the .sfs.ml or .sfs.em.ml for each .sfs file
    1. using a 2D-SFS as a prior, estimated using ngs2dSFS
    2. using marginal spectra as priors, estimated using optimSFS
    3. here we don't provide prior files, so we directly provide posterior probabilities (ANGSD+sfstools), and therefore we do not correct