ANGSD: Analysis of next generation Sequencing Data

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HWE and Inbreeding estimates: Difference between revisions

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Filipe G. Vieira  has been extending the ANGSD feature set by
=Site estimate of inbreeding coefficient (HWE test)=
# A method for estimating inbreeding (deviation from Hardy-Weinberg) based on output from ANGSD.
# Some parts of the ANGSD code (site frequency-sample allele frequency) will work for inbreeding estimates version 0.572+.


;NB If in doubt if a specific analysis will work please email and ask.
;-HWE_pval_F
==HWE and Inbreeding estimates==
 
For method details see [[inbreed|here]]
By choosing '''HWE_pval_F 1''', no sites will be filtered but the p-value along with the frequency, and F for the sites will be dumped in '''.hweF.gz''' file.
And the most recent version of the stand alone program is here https://github.com/fgvieira/ngsF.
 
=Estimation of individual inbreeding coefficients=
Filipe G. Vieira  has been extending the ANGSD feature set by a very fancy method for estimating individual inbreeding coefficients. Please see his website here: https://github.com/fgvieira/ngsF for the latest version which is utilising ANGSD output

Latest revision as of 15:59, 7 February 2018

Site estimate of inbreeding coefficient (HWE test)

-HWE_pval_F

By choosing HWE_pval_F 1, no sites will be filtered but the p-value along with the frequency, and F for the sites will be dumped in .hweF.gz file.

Estimation of individual inbreeding coefficients

Filipe G. Vieira has been extending the ANGSD feature set by a very fancy method for estimating individual inbreeding coefficients. Please see his website here: https://github.com/fgvieira/ngsF for the latest version which is utilising ANGSD output