NgsAdmix
This will contain the program called NGSadmix, which is a very nice tool for finding admixture. It is based on genotype likelihoods or genotype probabilities. It is a fancy multithreaded c/c++ program
Installation
wget popgen.dk/software/NGSadmix/ngsadmix32.cpp g++ ngsadmix32.cpp -O3 -lpthread -lz -o NGSadmix
Input Files
The current input files are the widely used beagle inputfiles, or beagle imputed outputfiles [1]. We recommend ANGSD for easy transformation of Next-generation sequencing data to beagle format.
Options
./NGSadmix Arguments: -likes Beagle likelihood filename -K Number of ancestral populations Optional: -fname Ancestral population frequencies -qname Admixture proportions -outfiles Prefix for output files -printInfo print ID and mean maf for the SNPs that were analysed Setup: -seed Seed for initial guess in EM -P Number of threads -method If 0 no acceleration of EM algorithm -misTol Tolerance for considering site as missing Stop chriteria: -tolLike50 Loglikelihood difference in 50 iterations -tol Tolerance for convergence -dymBound Use dymamic boundaries (1: yes (default) 0: no) -maxiter Maximum number of EM iterations Filtering -minMaf Minimum minor allele frequency -minLrt Minimum likelihood ratio value for maf>0 -minInd Minumum number of informative individuals
log
- v32 june 25-2013; modified code such that it now compiles on OSX
- v31 june 24-2013; First public version.