General info

This is the homepage for the PhD course "PhD course in analyses of genotyping and next-generation sequencing data in medical and population genetics 2016". The course is held by the Department of Biology, University of Copenhagen and is awarded with 5 ECTS point. To sign up, please contact us at The course is free for all PhD students at Danish universities (KU, AU, AUC, SDU and DTU). For all other PhD students there is a course fee of 200 US dollars. Food and accommodation are not included in the course.


The course is a comprehensive introduction to a number of topics and common research tools used in analyses of genetic data. Topics include: genetic drift, natural selection, population structure, Fst, linkage disequilibrium, relatedness, association mapping, GWAS, genotyping data, next-generation sequencing (NGS) data, 1000 genomes project data. The main focus will be on humans, but the methods are applicable for many other species as well. Lectures will be combined with hands-on computer exercises mostly using R and command line based programs.

Intended Learning Outcome

After the course the student should be able to


Time and place

The course will take place from August 22nd to August 26th 2016 at Biocenteret, Ole Maaloes Vej 5, 2200 Copenhagen N. All lectures and computer exercises will take place in room 4.0.02 (building 4, ground floor, room number 02).


You should bring a laptop to the course. We will log into a remove server from the laptop so any laptop will do regardless of operating system. However, please, if at all possible, make sure your computer can be connected to wired internet.

Course material

Handouts will be passed out during the course, but for some of the lectures there are articles/notes that should be read in advance - you can find them here. The slides used during the lectures will be made available right before the lectures.


Monday - Introduction to population genetics

Tuesday - Introduction to NGS data

Wednesday - Inference of demographic history and population structure

Thursday – Disease mapping

Friday - Detecting selection and genetic load


Participants who have participated actively in all parts of the course and completed all exercises satisfactorily will be awarded a certificate of completion at the end of the course. The work load corresponds to 5 ECTS points. Note that this workload includes one week of preparation. Reading material for this is available in the above course program.